Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427892 | 0.83 | MAPK1 (0.58) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12190105 | 0.82 | SMN1; SMN2 (0.60) | MAPTALDH1A1NPSR1LMNAHDAC1 | |
| SCHEMBL27716603 | 0.79 | PYGM (0.58) | MAPTNPC1RAB9AALDH1A1NPSR1 | |
| SCHEMBL20228918 | 0.78 | MAPT (0.76) | KDM4EMAPTHPGDNPC1RAB9A | |
| SCHEMBL29870304 | 0.78 | MAPT (0.76) | KDM4EMAPTHPGDNPC1RAB9A | |
| SCHEMBL7119403 | 0.75 | PYGM (0.76) | NPC1RAB9AALDH1A1SLC16A3KMT2A | |
| SCHEMBL8914972 | 0.74 | LMNA (0.69) | KDM4EMAPTHPGDNPC1RAB9A | |
| SCHEMBL493680 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KCNH2 | |
| SCHEMBL7360102 | 0.73 | BRD4 (0.69) | KDM4EMAPTHPGDNPC1RAB9A | |
| SCHEMBL3645013 | 0.73 | MEN1 (0.74) | KDM4EMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-10463611-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2019-11-05 | — | — | US | disclosed |
| US-9283283-B2 | Hyaluronic acid based hydrogel and use thereof in surgery | MERO S.R.L. (IT) | 2016-03-15 | — | — | US | disclosed |
| EP-2598180-B1 | HYALURONIC ACID BASED HYDROGEL AND USE THEREOF IN SURGERY | NOVAGENIT S R L (IT) | 2015-12-09 | — | — | EP | disclosed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140154313-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2014-06-05 | — | — | US | disclosed |
| WO-1995004533-A2 | TREATMENT OF RHEUMATOID ARTHRITIS WITH THALIDOMIDE ALONE OR IN COMBINATION WITH OTHER ANTI-INFLAMMATORY AGENTS | ANDRULIS PHARMACEUTICALS CORPORATION (US) | 1995-02-16 | — | — | WO | disclosed |
| EP-0355095-B1 | PHARMACOLOGICAL AGENT-LIPID SOLUTION PREPARATION | THE LIPOSOME COMPANY, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5154930-A | Pharmacological agent-lipid solution preparation | THE LIPOSOME COMPANY, INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0249561-B1 | COMPOSITIONS USING LIPOSOME-ENCAPSULATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | THE LIPOSOME COMPANY, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0289262-A2 | Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1988-11-02 | — | — | EP | disclosed |
| WO-1987007506-A1 | METHODS AND COMPOSITIONS USING LIPOSOME-ENCAPSULATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | THE LIPOSOME COMPANY, INC. (US) | 1987-12-17 | — | — | WO | disclosed |
| EP-0249561-A2 | Compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs | THE LIPOSOME COMPANY, INC. (US) | 1987-12-16 | — | — | EP | disclosed |