Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline1 SCHEMBL29447180 | 0.76 | MAPT (0.52) | CYP1A2KDM4EALDH1A1CYP2C19RAB9A | |
| Quinoxaline1 SCHEMBL1394500 | 0.76 | MAPT (0.52) | CYP1A2KDM4EALDH1A1CYP2C19RAB9A | |
| SCHEMBL23229339 | 0.73 | DYRK1A (0.36) | — | |
| SCHEMBL5247702 | 0.73 | ALDH1A1 (0.46) | CYP1A2KDM4EALDH1A1CYP2C19RAB9A | |
| SCHEMBL9006212 | 0.68 | MAOA (0.48) | CYP1A2KDM4EALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL29364974 | 0.67 | MAPT (0.62) | CYP1A2KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL103601 | 0.67 | MAPT (0.62) | CYP1A2KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL5793827 | 0.67 | DYRK1A (0.31) | — | |
| SCHEMBL29581806 | 0.67 | MAPT (0.71) | CYP1A2KDM4EALDH1A1CYP2C19RAB9A | |
| SCHEMBL2246928 | 0.67 | MAPT (0.71) | CYP1A2KDM4EALDH1A1CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1373270-B1 | TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER | MERCK PATENT GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | PFLUCKER FRANK | 2006-10-05 | — | — | US | disclosed |
| US-7101537-B2 | Tricyclic quinoxaline and quinoline derivatives as a UV filter | MERCK PATENTGESELLSCHAFT (DE) | 2006-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060222607-A1 | Tricyclic quinoxaline and quinoline derivatives as UV filters | RECQL, CUTA, NQO2 | CYP1A2 50/4885KDM4E 1602/4885ALDH1A1 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.