Quinoxaline1

Quinoxaline1

SCHEMBL29447180

Nc1n[nH]c2nc3ccccc3nc12

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.52
▸ KMT2A Q03164 4/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ CYP1A2 P05177 2/20 0.52
▸ CYP2C19 P33261 2/20 0.52
▸ TP53 P04637 2/20 0.52
▸ CYP3A4 P08684 2/20 0.52
▸ CCNT1 O60563 1/20 0.52
▸ CDK1 P06493 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CCNB1 P14635 1/20 0.52
▸ EIF2AK2 P19525 1/20 0.52
▸ CCNA2 P20248 1/20 0.52
▸ CCNE1 P24864 1/20 0.52
▸ CDK2 P24941 1/20 0.52
▸ GSK3B P49841 1/20 0.52
▸ CDK9 P50750 1/20 0.52
▸ CDK5 Q00535 1/20 0.52
▸ CDK5R1 Q15078 1/20 0.52
▸ KDM4E B2RXH2 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoxaline1 SCHEMBL1394500 1.00 MAPT (0.52) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL5251534 0.76 CYP1A2 (0.46) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL5247702 0.73 ALDH1A1 (0.46) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL10333619 0.73 GAA (0.57) MAPTKMT2AMEN1CYP3A4CDK1
SCHEMBL29515180 0.69 MAPT (0.62) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL13856236 0.68 KMT2A (0.63) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL29444102 0.67 MAPT (1.00) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL503252 0.67 MAPT (1.00) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL29402115 0.67 MAPT (0.71) MAPTKMT2AMEN1CYP1A2CYP2C19
SCHEMBL2246928 0.67 MAPT (0.71) MAPTKMT2AMEN1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431209-B Derived and mature hepatocyte types of liver stem cells and uses thereof 新加坡科技研究局 2023-02-10 — — CN claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
CN-114207111-B Method for producing skin-derived multipotent precursor cells 花王株式会社 2025-05-30 — — CN disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 — — WO disclosed
EP-4308153-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH NUCLEOTIDE REPEAT EXPANSION The General Hospital Corporation (US) 2024-01-24 — — EP disclosed
CN-108431209-B Derived and mature hepatocyte types of liver stem cells and uses thereof 新加坡科技研究局 2023-02-10 — — CN disclosed
WO-2022197857-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH NUCLEOTIDE REPEAT EXPANSION THE GENERAL HOSPITAL CORPORATION (US) 2022-09-22 — — WO disclosed
US-20220133740-A1 VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS Frequency Therapeutics, Inc. (US) 2022-05-05 — — US disclosed
CN-114207111-A Method for preparing skin-derived pluripotent precursor cells 花王株式会社 2022-03-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133740-A1 VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS WNT3A, WNT1, WNT3 MAPT 1671/4885KMT2A 674/4885MEN1 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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