Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525386 | 0.88 | BRD4 (0.47) | DYRK1ABRD4ALDH1A1MAPTCYP2A6 | |
| SCHEMBL525420 | 0.76 | EGFR (0.43) | ALDH1A1MAOAMAOBALOX15 | |
| SCHEMBL525638 | 0.75 | BRD4 (0.43) | BRD4NOTUMALDH1A1MAPTMAOA | |
| SCHEMBL525730 | 0.74 | SRC (0.43) | BRD4ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL525412 | 0.73 | PIM1 (0.38) | BRD4NOTUMCYP2A6MAOAMAOB | |
| SCHEMBL524971 | 0.73 | ALDH1A1 (0.40) | BRD4ALDH1A1MAPTMAOAMAOB | |
| SCHEMBL525548 | 0.70 | KDM4E (0.38) | NOTUMMAPTMAOAMAOB | |
| SCHEMBL525732 | 0.70 | ALOX15 (0.42) | BRD4ALDH1A1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL525511 | 0.70 | CHRNB4 (0.36) | BRD4ALDH1A1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL525198 | 0.70 | MAPT (0.36) | ALDH1A1MAPTMAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | claimed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | claimed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | claimed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | claimed |
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | disclosed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | disclosed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | MAVS, IRF3, IFNAR1 | DYRK1A 4366/4885BRD4 1780/4885NOTUM 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.