Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524971 | 0.87 | ALDH1A1 (0.40) | ALDH1A1SRCCYP1A2MAOAMAOB | |
| SCHEMBL525198 | 0.83 | MAPT (0.36) | ALDH1A1KDM4EHPGDCHRNB4CHRNA3 | |
| SCHEMBL525511 | 0.83 | CHRNB4 (0.36) | ALDH1A1CHRNB4CHRNA3MAOAMAOB | |
| SCHEMBL525548 | 0.83 | KDM4E (0.38) | KDM4EPARP10PARP11CHRNB4CHRNA3 | |
| SCHEMBL525732 | 0.83 | ALOX15 (0.42) | ALOX15ALOX12ALDH1A1KDM4EHPGD | |
| SCHEMBL525638 | 0.82 | BRD4 (0.43) | ALOX15ALOX12PIK3CAALDH1A1KDM4E | |
| SCHEMBL525730 | 0.82 | SRC (0.43) | PIK3CAALDH1A1HPGDPGRSLC6A3 | |
| SCHEMBL525555 | 0.80 | BRD4 (0.52) | ALDH1A1KDM4EHPGDKCNA3MIF | |
| SCHEMBL525561 | 0.80 | EGFR (0.38) | EGFRABL1ABL2ALOX15ALOX12 | |
| SCHEMBL524806 | 0.80 | TGFBR1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210290585-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | UNIV RAMOT (IL) | 2021-09-23 | — | — | US | claimed |
| EP-3544604-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | Ramot at Tel-Aviv University Ltd. (IL) | 2019-10-02 | — | — | EP | claimed |
| US-20190269644-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-09-05 | — | — | US | claimed |
| WO-2018096538-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2018-05-31 | — | — | WO | claimed |
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | claimed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | claimed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | claimed |
| EP-2420495-A1 | Novel derivatives useful as antiviral agents | Institut Pasteur (FR) | 2012-02-22 | — | — | EP | claimed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | claimed |
| US-20240325760-A1 | METHODS FOR DETECTING AND PREVENTING ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-10-03 | — | — | US | disclosed |
| EP-3864014-B1 | MALONATE SALT OF VARLITINIB | ASLAN PHARMACEUTICALS PTE LTD (SG) | 2023-07-05 | — | — | EP | disclosed |
| US-20210379070-A1 | MALONATE SALT OF VARLITINIB | ASLAN PHARMACEUTICALS PTE LTD (SG) | 2021-12-09 | — | — | US | disclosed |
| US-20210290585-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | UNIV RAMOT (IL) | 2021-09-23 | — | — | US | disclosed |
| US-11033524-B2 | Methods and compositions for treating disorders associated with cortico-hippocampal hyperactivity | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-06-15 | — | — | US | disclosed |
| WO-2018096538-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH CORTICO-HIPPOCAMPAL HYPERACTIVITY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2018-05-31 | — | — | WO | disclosed |
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | disclosed |
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | INSTITUT PASTEUR (FR) | 2013-08-15 | — | — | US | disclosed |
| EP-2598495-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Institut Pasteur (FR) | 2013-06-05 | — | — | EP | disclosed |
| EP-2420495-A1 | Novel derivatives useful as antiviral agents | Institut Pasteur (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2012014181-A1 | NOVEL DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INSTITUT PASTEUR (FR) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210886-A1 | Novel Derivatives Useful as Antiviral Agents | MAVS, IRF3, IFNAR1 | EGFR 3807/4885ABL1 1432/4885ABL2 4253/4885 |
| US-20210379070-A1 | MALONATE SALT OF VARLITINIB | KRAS, JAK1, JAK2 | EGFR 63/4885ABL1 20/4885ABL2 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.