SCHEMBL525396

SCHEMBL525396

O=C(O)Cc1cccc(CNC(=O)OCC2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
EPHX2 P34913 1/20 0.51
CASP3 P42574 2/20 0.43
OPRD1 P41143 1/20 0.43
FABP7 O15540 2/20 0.42
FABP5 Q01469 2/20 0.42
ITGB3 P05106 1/20 0.41
ITGAV P06756 1/20 0.41
ENPP2 Q13822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422053 1.00 KMT2A (0.56) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL1921443 0.89 KMT2A (0.50) KMT2AEPHX2ENPP2
SCHEMBL30640436 0.89 KMT2A (0.59) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL525564 0.89 KMT2A (0.59) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL18688054 0.88 EPHX2 (0.53) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL3177417 0.87 KMT2A (0.62) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL119110 0.86 KMT2A (0.53) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL29679265 0.86 KMT2A (0.53) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL29618948 0.86 KMT2A (0.53) KMT2AEPHX2OPRD1FABP7FABP5
SCHEMBL19633130 0.85 EPHX2 (0.66) KMT2AEPHX2CASP3OPRD1FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
WO-2023137366-A2 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON (US) 2023-07-20 WO disclosed
US-20230114807-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-04-13 US disclosed
US-11504441-B2 Radiolabeled compounds targeting the prostate-specific membrane antigen PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-11-22 US disclosed
EP-3986872-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN Provincial Health Services Authority (CA) 2022-04-27 EP disclosed
CN-114401947-A Radiolabeled compounds targeting prostate specific membrane antigen 省卫生服务机构 2022-04-26 CN disclosed
US-20210338851-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-11-04 US disclosed
US-20210198278-A1 SECO MACROLIDE COMPOUNDS SELVITA D.O.O. (HR) 2021-07-01 US disclosed
WO-2020252598-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-12-24 WO disclosed
EP-2598157-B1 CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION SANOFI SA (FR) 2016-10-12 EP disclosed
US-9073975-B2 Cyclic peptides, their preparation and their use as inhibitors of the platelet adhesion SANOFI (FR) 2015-07-07 US disclosed
US-20140011734-A1 CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION SANOFI (FR) 2014-01-09 US disclosed
EP-2598157-A1 CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION SANOFI (FR) 2013-06-05 EP disclosed
WO-2012013709-A1 CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION SANOFI (FR) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140011734-A1 CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION F12, F11, F13B KMT2A 4818/4885EPHX2 2931/4885CASP3 1903/4885
US-20210338851-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FOLH1, KLK3, PSMA3 KMT2A 1402/4885EPHX2 2303/4885CASP3 2161/4885
US-20210198278-A1 SECO MACROLIDE COMPOUNDS SEC61B, SEC16A, SEC61A1 KMT2A 4255/4885EPHX2 1144/4885CASP3 1238/4885
US-11504441-B2 Radiolabeled compounds targeting the prostate-specific membrane antigen FOLH1, KLK3, PSMA3 KMT2A 1402/4885EPHX2 2303/4885CASP3 2161/4885
US-20230114807-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FOLH1, KLK3, PSMA3 KMT2A 1402/4885EPHX2 2303/4885CASP3 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.