Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187913 | 0.88 | MMP2 (0.36) | — | |
| SCHEMBL5260323 | 0.73 | ACE (0.42) | ACEPOLB | |
| SCHEMBL5256022 | 0.72 | ACE (0.41) | ACEPOLB | |
| SCHEMBL19470993 | 0.68 | DRD1 (0.57) | CYP3A4 | |
| SCHEMBL17674610 | 0.68 | DRD1 (0.57) | CYP3A4 | |
| SCHEMBL5254943 | 0.66 | NPC1 (0.38) | ACEL3MBTL1 | |
| SCHEMBL5023851 | 0.65 | ACE (0.66) | ACE | |
| SCHEMBL5185349 | 0.65 | MMP2 (0.40) | POLB | |
| SCHEMBL5253676 | 0.64 | ACE (0.36) | ACEPOLBCYP3A4 | |
| SCHEMBL5257429 | 0.64 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |