Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967580 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3KCNH2L3MBTL1 | |
| SCHEMBL6969342 | 0.81 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3KCNH2L3MBTL1 | |
| SCHEMBL1290745 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2GABRA5 | |
| SCHEMBL4912629 | 0.79 | GPR119 (0.42) | EPHX1 | |
| SCHEMBL297266 | 0.78 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3KCNH2GABRA5 | |
| SCHEMBL27348780 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3KCNH2GABRA5 | |
| Hydrochloric Acid SCHEMBL3740415 | 0.77 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3KCNH2GABRA5 | |
| SCHEMBL8851041 | 0.76 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL9732660 | 0.76 | GABRA5 (0.44) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL18928228 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3KCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833792-A1 | SUBSTITUTED PIPERIDINE COMPOUNDS FOR USE AS CCR5 MODULATORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006067385-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |