Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187180 | 0.91 | KMT2A (0.38) | HTR1ASLC6A2SLC6A4SLC6A3SIRT1 | |
| SCHEMBL4696919 | 0.83 | MEN1 (0.36) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL5253702 | 0.77 | HTR1A (0.38) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL5252503 | 0.75 | MRGPRX4 (0.33) | MRGPRX4S1PR5 | |
| SCHEMBL4144345 | 0.74 | MEN1 (0.38) | — | |
| SCHEMBL5185631 | 0.72 | KMT2A (0.39) | HTR1ASLC6A2SLC6A4SLC6A3MRGPRX4 | |
| SCHEMBL4696338 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL5253676 | 0.72 | ACE (0.36) | — | |
| SCHEMBL5255876 | 0.70 | MEN1 (0.37) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL5255804 | 0.70 | ALOX15 (0.36) | KDM1AMRGPRX4S1PR5SIRT1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1399444-A2 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100860-A2 | HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-12-19 | — | — | WO | disclosed |