Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557279 | 0.89 | CYP3A4 (0.53) | CYP3A4CA1CA7CA12CA2 | |
| SCHEMBL2928543 | 0.89 | CYP3A4 (0.53) | CYP3A4CA1CA7CA12CA2 | |
| SCHEMBL13903446 | 0.80 | CYP3A4 (0.46) | CYP3A4ALDH1A1CA1CA7CA12 | |
| SCHEMBL10516399 | 0.79 | PDE3B (0.44) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL15119597 | 0.78 | ADORA3 (0.43) | CYP3A4CA1CA12CA2CA9 | |
| SCHEMBL5251983 | 0.78 | CYP2A6 (0.56) | ALDH1A1CA1CA7CA12CA9 | |
| SCHEMBL28403462 | 0.77 | KDM4E (0.51) | ALDH1A1MEN1KMT2AMAOBPOLB | |
| SCHEMBL11496731 | 0.75 | ALDH1A1 (0.63) | MCL1CYP3A4PDE4APDE4BPDE4C | |
| SCHEMBL9079018 | 0.75 | KMT2A (0.49) | CYP3A4ALDH1A1PDE1APDE1BPDE3B | |
| SCHEMBL10426890 | 0.74 | CYP3A4 (0.48) | CYP3A4CA1CA7CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839155-B2 | Organic semiconducting compounds | RAYNERGY TEK INC. (TW) | 2023-12-05 | — | — | US | disclosed |
| US-11839155-B2 | Organic semiconducting compounds | RAYNERGY TEK INC. (TW) | 2023-12-05 | — | — | US | disclosed |
| US-11839155-B2 | Organic semiconducting compounds | RAYNERGY TEK INC. (TW) | 2023-12-05 | — | — | US | disclosed |
| US-20220320445-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | RAYNERGY TEK INC. (TW) | 2022-10-06 | — | — | US | disclosed |
| US-11008282-B2 | Bicyclic-compounds for use as a medicament, in particular for treatment of parkinson's disease | KOESTER HUBERT (CH) | 2021-05-18 | — | — | US | disclosed |
| WO-2017103278-A1 | NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE | CAPROTEC BIOANALYTICS GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-1242382-B1 | TRICYCLIC PROTEIN KINASE INHIBITORS | WYETH CORP (US) | 2007-02-07 | — | — | EP | disclosed |
| US-20060247217-A1 | Tricyclic protein kinase inhibitors | BERGER DAN M | 2006-11-02 | — | — | US | disclosed |
| US-7105531-B2 | Tricyclic protein kinase inhibitors | WYETH (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040110762-A1 | Tricyclic protein kinase inhibitors | WYETH | 2004-06-10 | — | — | US | disclosed |
| US-6638929-B2 | Compounds containing nicotinonitrile rings; anticarcinogenic and -tumor agents; polycystic kidney disease and colonic polyps; antiproliferative agents; angiogenesis inhibitors; restenosis; atherosclerosis; angiofibromas; hemangiomas; | WYETH | 2003-10-28 | — | — | US | disclosed |
| EP-1242382-A1 | TRICYCLIC PROTEIN KINASE INHIBITORS | Wyeth (US) | 2002-09-25 | — | — | EP | disclosed |
| US-20010051620-A1 | Tricyclic protein kinase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-12-13 | — | — | US | disclosed |
| WO-2001047892-A1 | TRICYCLIC PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11839155-B2 | Organic semiconducting compounds | OCIAD2, OCIAD1, OSTC | MCL1 2121/4885CYP3A4 150/4885PDE4A 3442/4885 |
| US-20040110762-A1 | Tricyclic protein kinase inhibitors | CDK1, CDKN1A, CDK2 | MCL1 155/4885CYP3A4 1595/4885PDE4A 3344/4885 |
| US-20060247217-A1 | Tricyclic protein kinase inhibitors | CDK1, CDKN1A, CDK2 | MCL1 181/4885CYP3A4 1338/4885PDE4A 3125/4885 |
| US-20010051620-A1 | Tricyclic protein kinase inhibitors | CDK1, CHEK1, ABL1 | MCL1 511/4885CYP3A4 2811/4885PDE4A 2015/4885 |
| US-20220320445-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | OCIAD2, OCIAD1, OSTC | MCL1 2121/4885CYP3A4 150/4885PDE4A 3442/4885 |
| US-11008282-B2 | Bicyclic-compounds for use as a medicament, in particular for treatment of parkinson's disease | COMT, PNMT, DBH | MCL1 4567/4885CYP3A4 133/4885PDE4A 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.