SCHEMBL9375555

SCHEMBL9375555

C1=NCCN1c1ncccn1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 2/20 0.31
KMT2A Q03164 2/20 0.31
NPC1 O15118 1/20 0.30
MEN1 O00255 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105023 0.68 SIGMAR1 (0.41) KDM4ELMNAMAPTPOLBHTT
SCHEMBL6272216 0.68 SIGMAR1 (0.41) KDM4ELMNAMAPTPOLBHTT
SCHEMBL10757283 0.68 ALDH1A1 (0.39) KDM4EALDH1A1LMNAMAPTHTT
Hydrochloric Acid SCHEMBL27446824 0.67 NPC1 (0.43) KDM4ELMNAMAPTPOLBHTT
SCHEMBL6663539 0.64
SCHEMBL10498542 0.64 LMNA (0.70) KDM4EALDH1A1LMNAMAPTUSP2
SCHEMBL18228601 0.64 KDM4E (0.38) KDM4EALDH1A1LMNAMAPTUSP2
SCHEMBL1886690 0.63 ADRB1 (0.43) ALDH1A1LMNAMAPTTSHRKMT2A
SCHEMBL10168488 0.63 KCNH2 (0.33)
Hydrochloric Acid SCHEMBL12502872 0.63 NOTUM (0.33) ALDH1A1LMNACYP2D6NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595015-A1 Imidazolinyl-pyrimidines and their use as herbicides BAYER AG (DE) 1994-05-04 EP claimed
EP-0581086-A1 Imidazolynyl-pyrimidines and their use as herbicides and fungicides BAYER AG (DE) 1994-02-02 EP claimed
US-5244865-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1993-09-14 US claimed
EP-0517052-A1 Substituted imidazolinyl-pyrimidines BAYER AG (DE) 1992-12-09 EP claimed
JP-6199836-A None JP disclosed
JP-6184138-A None JP disclosed
CN-111201227-A Imidazolidine pyrimidinium compounds for combating animal pests 巴斯夫欧洲公司 2020-05-26 CN disclosed
CN-101400651-A Diaryl piperidines as CB1 modulators SCHERING CORP (US) 2009-04-01 CN disclosed
JP-H06199836-A IMIDAZOLINYL-PYRIMIDINES BAYER AG 1994-07-19 JP disclosed
JP-H06184138-A IMIDAZOLINYL-PYRIMIDINES BAYER AG 1994-07-05 JP disclosed
EP-0595015-A1 Imidazolinyl-pyrimidines and their use as herbicides BAYER AG (DE) 1994-05-04 EP disclosed
EP-0595015-A1 Imidazolinyl-pyrimidines and their use as herbicides BAYER AG (DE) 1994-05-04 EP disclosed
EP-0581086-A1 Imidazolynyl-pyrimidines and their use as herbicides and fungicides BAYER AG (DE) 1994-02-02 EP disclosed
EP-0581086-A1 Imidazolynyl-pyrimidines and their use as herbicides and fungicides BAYER AG (DE) 1994-02-02 EP disclosed
EP-0581086-A1 Imidazolynyl-pyrimidines and their use as herbicides and fungicides BAYER AG (DE) 1994-02-02 EP disclosed
US-5244865-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
US-5244865-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
EP-0517052-A1 Substituted imidazolinyl-pyrimidines BAYER AG (DE) 1992-12-09 EP disclosed
EP-0517052-A1 Substituted imidazolinyl-pyrimidines BAYER AG (DE) 1992-12-09 EP disclosed
EP-0517052-A1 Substituted imidazolinyl-pyrimidines BAYER AG (DE) 1992-12-09 EP disclosed