SCHEMBL5258191

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5256868	0.84	VDR (0.48)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL5261671	0.82	MAPT (0.59)	VDRPPARAMEN1KMT2AMAPT
	SCHEMBL10836045	0.80	VDR (0.56)	VDRPPARAMEN1KMT2AMAPT
	SCHEMBL5258148	0.78	VDR (0.56)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL27493058	0.76	VDR (0.57)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL5259560	0.76	VDR (0.47)	VDRPPARAMEN1KMT2AMAPT
	SCHEMBL5257153	0.75	VDR (0.57)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL30995727	0.72	CNR1 (0.77)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL5260961	0.71	KIF11 (0.47)	VDRMEN1KMT2AMAPTKDM4E
	SCHEMBL10413203	0.71	VDR (0.57)	VDRMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.