Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 16/20 | 0.36 |
| ▸ | EDNRA | P25101 | 16/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313941 | 0.90 | EDNRB (0.34) | EDNRBEDNRAKDM4EALDH1A1NR1H2 | |
| SCHEMBL5261114 | 0.87 | EDNRB (0.33) | EDNRBEDNRAKDM4EALDH1A1 | |
| SCHEMBL5186385 | 0.76 | EDNRB (0.32) | EDNRBEDNRA | |
| SCHEMBL25254031 | 0.65 | ALOX5 (0.42) | NR1H2NR1H3 | |
| SCHEMBL25296546 | 0.65 | ALOX5 (0.42) | NR1H2NR1H3 | |
| SCHEMBL4692611 | 0.65 | NR1H2 (0.30) | NR1H2NR1H3 | |
| SCHEMBL29002093 | 0.64 | AKR1C3 (0.54) | EDNRBEDNRAKDM4EALDH1A1LMNA | |
| SCHEMBL5258507 | 0.64 | TSHR (0.50) | EDNRBEDNRAKDM4EALDH1A1LMNA | |
| SCHEMBL5252111 | 0.63 | KMT2A (0.43) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL8986465 | 0.62 | PKM (0.41) | KDM4EALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |