Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | NSD2 | O96028 | 1/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.65 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230268 | 0.81 | NPC1 (0.60) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL18174173 | 0.81 | POLB (0.59) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL13528571 | 0.79 | NPC1 (1.00) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL25271063 | 0.79 | POLB (0.52) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL25719744 | 0.79 | NPC1 (0.52) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL2069697 | 0.79 | POLB (0.52) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL11831197 | 0.79 | POLB (0.52) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL18951942 | 0.78 | POLB (0.50) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL28135935 | 0.76 | KDM4E (0.58) | POLBRAB9ANPC1APAF1NSD2 | |
| SCHEMBL31064873 | 0.75 | ALDH1A1 (0.65) | POLBRAB9ANPC1APAF1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371422-B2 | Fluorine-containing pyrimidine compound and manufacturing method for same | UNIMATEC CO., LTD. (JP) | 2025-07-29 | — | — | US | disclosed |
| US-20240150329-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND MANUFACTURING METHOD FOR SAME | UNIMATEC CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-116143763-A | GAS41 targeting compound, GAS41 inhibitor and pharmaceutical composition and application thereof | 清华大学 | 2023-05-23 | — | — | CN | disclosed |
| EP-4052759-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND MANUFACTURING METHOD FOR SAME | Unimatec Co., Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-114585618-A | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021085540-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND MANUFACTURING METHOD FOR SAME | ユニマテック株式会社 | 2021-05-06 | — | — | WO | disclosed |
| EP-3555095-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |
| US-20190295778-A1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF | FUJIFILM CORPORATION (JP) | 2019-09-26 | — | — | US | disclosed |
| CN-105814049-B | Fused tricyclic imdazole derivatives as TNF active regulator | UCB生物制药私人有限公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-105814047-B | Fused tricyclic imdazole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-10-19 | — | — | CN | disclosed |
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |
| JP-2006022073-A | FURYLPYRIMIDINE DERIVATIVE OR SALT THEREOF, AND APPLICATION THEREOF | TAIHO YAKUHIN KOGYO KK | 2006-01-26 | — | — | JP | disclosed |
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |
| US-6642237-B1 | Inhibitors of HIV protease and inhibitors of HIV replication, used in the prevention or treatment of infection by HIV and treatment for AIDS | MERCK & CO., INC. | 2003-11-04 | — | — | US | disclosed |
| US-6583154-B1 | Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines | AMGEN INC. | 2003-06-24 | — | — | US | disclosed |
| EP-1242426-A1 | GAMMA-HYDROXY-2-(FLUOROALKYLAMINOCARBONYL)-1-PIPERAZINEPENTANAMIDES AS HIV PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001038332-A1 | GAMMA-HYDROXY-2-(FLUOROALKYLAMINOCARBONYL)-1-PIPERAZINEPENTANAMIDES AS HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371422-B2 | Fluorine-containing pyrimidine compound and manufacturing method for same | CNOT1, FXR1, CYP1B1 | POLB 775/4885RAB9A 3589/4885NPC1 765/4885 |
| US-20190295778-A1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF | LEF1, MLLT3, CRY1 | POLB 2701/4885RAB9A 2270/4885NPC1 4253/4885 |
| US-20240150329-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND MANUFACTURING METHOD FOR SAME | CNOT1, FXR1, CYP1B1 | POLB 775/4885RAB9A 3589/4885NPC1 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.