Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4842251 | 0.91 | TPH1 (0.37) | FYNHPGDHPSENPBWR1BRAF | |
| SCHEMBL4834899 | 0.84 | MMP2 (0.43) | HPGDHPSENPC1RAB9AKMT2A | |
| SCHEMBL5259906 | 0.82 | LMNA (0.43) | HPSENPC1RAB9AKMT2AKDR | |
| SCHEMBL5260119 | 0.80 | ALDH1A1 (0.42) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5256155 | 0.80 | NPC1 (0.42) | HPGDHPSEDYRK1ADYRK1BPIM1 | |
| SCHEMBL5257452 | 0.80 | NPC1 (0.34) | HPGDCLK4HPSEPIM1NPC1 | |
| SCHEMBL5258985 | 0.80 | MAOB (0.46) | HPGDNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL4843978 | 0.80 | NPC1 (0.53) | CLK4HPSEDYRK1ADYRK1BCLK1 | |
| SCHEMBL4834208 | 0.80 | HDAC6 (0.43) | HPGDHPSEKMT2AKDM4EALDH1A1 | |
| SCHEMBL5258008 | 0.79 | HPSE (0.35) | HPGDCLK4HPSENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100358893-C | Certain novel imidazopyridines and uses thereof | ASTRAZENECA AB (SE) | 2008-01-02 | — | — | CN | claimed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |
| CN-1684964-A | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2005-10-19 | — | — | CN | claimed |
| CN-100358893-C | Certain novel imidazopyridines and uses thereof | ASTRAZENECA AB (SE) | 2008-01-02 | — | — | CN | disclosed |
| CN-1684964-A | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2005-10-19 | — | — | CN | disclosed |