SCHEMBL5259883

SCHEMBL5259883

Oc1ccc2[nH]cc(O)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 8/20 0.56
HTR1A P08908 7/20 0.55
HTR2A P28223 5/20 0.55
CYP2C9 P11712 4/20 0.55
HTR2B P41595 4/20 0.55
CYP2D6 P10635 4/20 0.55
HTR1D P28221 4/20 0.55
TSHR P16473 3/20 0.55
CYP1A2 P05177 3/20 0.55
CYP3A4 P08684 3/20 0.55
HTR1B P28222 2/20 0.55
HTR7 P34969 2/20 0.55
HTR3E A5X5Y0 1/20 0.55
HTR3B O95264 1/20 0.55
DRD1 P21728 1/20 0.55
HTR1E P28566 1/20 0.55
HTR1F P30939 1/20 0.55
DRD3 P35462 1/20 0.55
RECQL P46063 1/20 0.55
HTR3A P46098 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30686491 1.00 HTR2C (0.56) HTR2CHTR1AHTR2ACYP2C9HTR2B
Phosphoric Acid SCHEMBL6372496 0.90 NPSR1 (0.50) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL1180662 0.84 NPSR1 (0.51) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL3263472 0.82 HTR2C (0.59) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL5435851 0.82 HTR2C (0.56) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL21291518 0.80 HTR2C (0.55) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL23612158 0.78 HTR2C (0.56) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL17439076 0.78 F7 (0.59) HTR2ASLC6A4
SCHEMBL5197534 0.78 HTR2C (0.53) HTR2CHTR1AHTR2ACYP2C9HTR2B
SCHEMBL21623874 0.78 HPGD (0.50) HTR2CHTR1AHTR2ACYP2C9HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271186-B1 HYDROXYINDOLES AND THEIR USE IN DYEING REPLIGEN CORPORATION (US) 1992-12-30 EP claimed
US-20240240390-A1 PROCESS FOR DYEING TEXTILES AND ENZYMES USED THEREIN SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. (TR) 2024-07-18 US disclosed
CN-114222841-B Textile dyeing process 尚科纺织企业工业及贸易公司 2024-04-12 CN disclosed
US-11920290-B2 Process for dyeing textiles and enzymes used therein SANKO TEKSTIL ISLETMELERI SAN. VE TIC A.S. (TR) 2024-03-05 US disclosed
CN-117159588-B Cell therapy method for treating osteoarthritis by umbilical cord mesenchymal stem cells 北京国卫生物科技有限公司 2024-02-13 CN disclosed
CN-117159589-B Stem cell treatment method for treating systemic lupus erythematosus 北京国卫生物科技有限公司 2024-02-13 CN disclosed
CN-117159589-A Stem cell treatment method for treating systemic lupus erythematosus 北京国卫生物科技有限公司 2023-12-05 CN disclosed
CN-117159588-A Novel cell therapy method for treating osteoarthritis by umbilical cord mesenchymal stem cells 北京国卫生物科技有限公司 2023-12-05 CN disclosed
US-20230001024-A1 CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY 2023-01-05 US disclosed
EP-4003363-A1 CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF North Carolina State University (US) 2022-06-01 EP disclosed
WO-2021016537-A1 CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2021-01-28 WO disclosed
WO-2021016548-A1 POLYIODIDE BINDING COMPOUNDS AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2021-01-28 WO disclosed
WO-2021013371-A1 PROCESS FOR DYEING TEXTILES SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. (TR) 2021-01-28 WO disclosed
WO-2020015839-A1 PROCESS AND APPARATUS FOR DYEING TEXTILES SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. (TR) 2020-01-23 WO disclosed
CN-108129375-A Compound and preparation method thereof and the application in tumor drug resistance reversal agent is prepared 中山大学 2018-06-08 CN disclosed
CN-101563337-A Indole compounds MICROBIA INC (US) 2009-10-21 CN disclosed
EP-1765267-A1 INITIAL PHENYLPROPANEDIOL DYE PRODUCTS Henkel Kommanditgesellschaft auf Aktien (DE) 2007-03-28 EP disclosed
WO-2006002712-A1 INITIAL PHENYLPROPANEDIOL DYE PRODUCTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-01-12 WO disclosed
CN-1688549-A Compound having TGF-beta inhibitory activity and medicinal composition containing the same KIRIN BREWERY (JP) 2005-10-26 CN disclosed
CN-1141633-A 4-heterocyclic substituted quinazoline derivatives, process for their preparation and their use as anticancer agents PFIZER (US) 1997-01-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230001024-A1 CROSS-LINKING COMPOUNDS AND METHODS OF USE THEREOF AOX1, MTCL3, COL1A1 HTR2C 3722/4885HTR1A 4204/4885HTR2A 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.