Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258634 | 1.00 | KDR (0.38) | KDRHIF1AKDM4EMAPTHTR3A | |
| SCHEMBL28478338 | 0.71 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL28478339 | 0.71 | KDM4E (0.43) | KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7685070 | 0.70 | KDM4E (0.51) | KDM4EMAPTHTR3AALDH1A1HPGD | |
| SCHEMBL7685072 | 0.70 | KDM4E (0.51) | KDM4EMAPTHTR3AALDH1A1HPGD | |
| SCHEMBL16255877 | 0.70 | KDM4E (0.51) | KDM4EMAPTHTR3AALDH1A1HPGD | |
| SCHEMBL16255397 | 0.68 | FURIN (0.50) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17423838 | 0.68 | KMO (0.46) | KDM4EMAPTHTR3AMEN1KMT2A | |
| SCHEMBL10253915 | 0.65 | KDM4C (0.49) | HIF1AKDM4EMAPTMCL1ALDH1A1 | |
| SCHEMBL9960248 | 0.65 | ELANE (0.57) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844993-B1 | PESTICIDAL INDAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |