Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 15/20 | 0.51 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19332530 | 0.82 | CA2 (0.51) | FBP1 | |
| SCHEMBL2009157 | 0.81 | FBP1 (0.72) | FBP1 | |
| SCHEMBL387144 | 0.80 | FBP1 (0.74) | CYP2C9FBP1 | |
| SCHEMBL5032592 | 0.80 | CYP19A1 (0.60) | — | |
| SCHEMBL8589883 | 0.79 | ALDH1A1 (0.67) | FBP1LARS1 | |
| SCHEMBL6297904 | 0.76 | TSHR (0.64) | FBP1 | |
| SCHEMBL8541021 | 0.76 | FBP1 (0.51) | FBP1 | |
| SCHEMBL15054822 | 0.76 | F2 (0.51) | FBP1 | |
| SCHEMBL13996548 | 0.76 | CYP2C9 (0.70) | CYP2C9 | |
| SCHEMBL5050574 | 0.75 | F2 (0.61) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599468-B1 | 1,2,3-TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO SUCH AS DIABETES AND HYPERGLYCEMIA | ARENA PHARM INC (US) | 2007-10-03 | — | — | EP | disclosed |