Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297904 | 0.84 | TSHR (0.64) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL27714135 | 0.81 | FBP1 (0.61) | ALDH1A1FBP1KMT2A | |
| SCHEMBL18028832 | 0.81 | KAT6A (0.51) | TSHRPOLBLMNAKAT6AHTR6 | |
| SCHEMBL8549266 | 0.80 | F2 (0.51) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8589883 | 0.80 | ALDH1A1 (0.67) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL23918994 | 0.80 | LMNA (0.65) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6158564 | 0.80 | MEN1 (0.69) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL15054822 | 0.80 | F2 (0.51) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL9302922 | 0.80 | F2 (0.51) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL370189 | 0.79 | CA2 (0.56) | LMNACA2CA1CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437062-B | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114437062-A | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-1888045-A2 | ORAL PHARMACEUTICAL COMPOSITION FOR TREATING A COX-2 MEDIATED CONDITION | FLAMEL TECHNOLOGIE, Société Anonyme (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007036809-A2 | NOVEL ACETYLSALICYLIC ACID FORMULATIONS | FLAMEL TECHNOLOGIES S.A. (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-1551403-A1 | 5-SUBSTITUTED 2H-PYRAZONE-3-CARBOXYLIC ACID DERIVATIVES AS ANTILIPOLYTIC AGENTS FOR THE TREATMENT OF METABOLIC-RELATED DISORDERS SUCH AS DYSLIPIDEMIA | Arena Pharmaceuticals, Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004032928-A1 | 5-SUBSTITUTED 2H-PYRAZONE-3-CARBOXYLIC ACID DERIVATIVES AS ANTILIPOLYTIC AGENTS FOR THE TREATMENT OF METABOLIC-RELATED DISORDERS SUCH AS DYSLIPIDEMIA | ARENA PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |