Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794954 | 0.97 | TSHR (0.52) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL6013957 | 0.92 | KIF11 (0.56) | TSHRLMNATYRBCHEACHE | |
| Magnesium Chloride Anhydrous SCHEMBL28561945 | 0.89 | TSHR (0.46) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL6745011 | 0.85 | ALDH1A1 (0.63) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL424728 | 0.83 | TSHR (0.73) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL5390560 | 0.77 | PDE2A (0.50) | TSHRLMNATYRHPGDHSD17B10 | |
| SCHEMBL128463 | 0.77 | MEN1 (0.39) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL17844878 | 0.77 | TSHR (0.32) | TSHRLMNATYRHPGDHSD17B10 | |
| Hydrogen Peroxide SCHEMBL28677809 | 0.76 | LMNA (0.71) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL6398106 | 0.75 | ALDH1A1 (0.41) | TSHRLMNATYRKIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3308 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| CN-118239883-A | Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor | 江苏联环药业股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| US-20240182430-A1 | SYNTHESIS OF SUBSTITUTED PYRAZINES | MEDIBEACON INC. | 2024-06-06 | — | — | US | claimed |
| WO-2024118535-A1 | SYNTHESIS AND PURIFICATION OF SUBSTITUTED PYRAZINES | MEDIBEACON INC. (US) | 2024-06-06 | — | — | WO | claimed |
| CN-117185925-B | Preparation method of polysubstituted aryl carboxylate compound | 江西师范大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116284021-B | Compounds having therapeutic effect on bladder cancer | 湖南大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117430584-A | Novel pyrazole-pyridine derivatives, and preparation method and application thereof | 河北农业大学 | 2024-01-23 | — | — | CN | claimed |
| CN-117185925-A | Preparation method of polysubstituted aryl carboxylate compound | 江西师范大学 | 2023-12-08 | — | — | CN | claimed |
| CN-117143003-A | Fluoroalkyl-substituted bisindolol and synthesis method thereof | 宁波大学 | 2023-12-01 | — | — | CN | claimed |
| CN-116874383-A | Benzophenone LED visible light initiator and preparation method and application thereof | 贵州师范学院 | 2023-10-13 | — | — | CN | claimed |
| US-4235920-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | claimed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | claimed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| US-4128651-A | Bis-quaternary pyridinium-2-aldoxime salts and a process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-12-05 | — | — | US | claimed |
| US-4078068-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | claimed |
| US-4078067-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | claimed |
| US-4076826-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1978-02-28 | — | — | US | claimed |