Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.32 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657194 | 0.88 | HSP90AA1 (0.41) | P2RX7KMT2APKMHTTGFER | |
| Pyrrole SCHEMBL3131650 | 0.80 | LMNA (0.40) | KMT2ALMNAALDH1A1CYP1A2L3MBTL1 | |
| Pyrrole SCHEMBL1706242 | 0.75 | P2RX7 (0.51) | P2RX7KMT2APKMHTTGFER | |
| SCHEMBL12470613 | 0.72 | HSP90AA1 (0.40) | P2RX7KMT2APKMHSP90AA1KDR | |
| SCHEMBL8390998 | 0.72 | HSP90AA1 (0.45) | P2RX7KMT2AHSP90AA1KDRBRAF | |
| SCHEMBL2788170 | 0.72 | P2RX7 (0.43) | P2RX7KMT2APKMHTTGFER | |
| SCHEMBL30606626 | 0.71 | KMT2A (0.40) | P2RX7KMT2AHSP90AA1LMNACYP1A2 | |
| SCHEMBL28145746 | 0.71 | KMT2A (0.40) | P2RX7KMT2AHSP90AA1LMNACYP1A2 | |
| SCHEMBL10376804 | 0.71 | KMT2A (0.49) | KMT2AHTTGFERLMNAALDH1A1 | |
| SCHEMBL30575119 | 0.70 | HSP90AA1 (0.39) | P2RX7KMT2APKMHSP90AA1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |