Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | DRD3 | P35462 | 4/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 11/20 | 0.57 |
| ▸ | HTR2C | P28335 | 11/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318620 | 0.86 | DRD2 (0.61) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL14339849 | 0.86 | DRD3 (0.68) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5264300 | 0.85 | DRD2 (0.66) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5265021 | 0.82 | HTR1A (0.48) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5266898 | 0.81 | DRD2 (0.49) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5317525 | 0.81 | HTR1A (0.59) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5263145 | 0.81 | DRD2 (0.49) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL5463279 | 0.79 | DRD2 (0.48) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| SCHEMBL7057755 | 0.75 | DRD2 (0.74) | DRD2DRD3ADRA1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7534187 | 0.73 | DRD2 (0.93) | DRD2DRD3ADRA1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DRD2 64/4885DRD3 176/4885ADRA1A 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.