Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 14/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271807 | 0.82 | KCNA5 (0.54) | GAAHPGDTSHRMMP2MEN1 | |
| SCHEMBL5267782 | 0.81 | GAA (0.55) | GAAHPGDTSHRMMP2MEN1 | |
| SCHEMBL5274014 | 0.80 | ALDH1A1 (0.54) | PKLRGAAGFERHPGDTSHR | |
| SCHEMBL5265907 | 0.79 | MEN1 (0.57) | GAAHPGDMMP2MEN1KMT2A | |
| SCHEMBL5271053 | 0.77 | L3MBTL1 (0.51) | GAAHPGD | |
| SCHEMBL5270341 | 0.77 | MEN1 (0.54) | PKLRGAAHPGDMMP2MEN1 | |
| SCHEMBL5273212 | 0.76 | ALDH1A1 (0.47) | GAATSHRMEN1KMT2A | |
| SCHEMBL5270886 | 0.75 | SMN1; SMN2 (0.57) | GAAHPGDMMP2MEN1KMT2A | |
| SCHEMBL5265851 | 0.74 | MCL1 (0.48) | HPGDTSHRMEN1KMT2A | |
| SCHEMBL5269971 | 0.74 | L3MBTL1 (0.50) | GAAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |