Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271053 | 0.93 | L3MBTL1 (0.51) | L3MBTL1RXFP1HSD17B10GAAHPGD | |
| SCHEMBL5266983 | 0.86 | RXFP1 (0.49) | L3MBTL1RXFP1HSD17B10GAAMAPT | |
| SCHEMBL5274022 | 0.86 | L3MBTL1 (0.46) | L3MBTL1RXFP1HSD17B10MAPK1GAA | |
| SCHEMBL5271765 | 0.86 | ALDH1A1 (0.48) | L3MBTL1RXFP1HSD17B10MAPTKMT2A | |
| SCHEMBL5267751 | 0.86 | NPC1 (0.56) | L3MBTL1HSD17B10GAAMEN1MAPT | |
| SCHEMBL5273212 | 0.85 | ALDH1A1 (0.47) | L3MBTL1RXFP1HSD17B10GAAMEN1 | |
| SCHEMBL5268091 | 0.84 | LMNA (0.55) | L3MBTL1HSD17B10GAAMAPTKMT2A | |
| SCHEMBL5265743 | 0.83 | ALDH1A1 (0.53) | L3MBTL1GAAMEN1MAPTHTT | |
| SCHEMBL5272349 | 0.80 | MEN1 (0.47) | ACLYMAPK1GAAMEN1MAPT | |
| SCHEMBL4284633 | 0.79 | KMT2A (0.49) | ACLYMAPK1GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |