Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267782 | 0.86 | GAA (0.55) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5270341 | 0.85 | MEN1 (0.54) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5273547 | 0.85 | TSHR (0.49) | MEN1KMT2AALDH1A1KCNA5SLC16A3 | |
| SCHEMBL5271807 | 0.84 | KCNA5 (0.54) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5270886 | 0.84 | SMN1; SMN2 (0.57) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5274014 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5270764 | 0.79 | KMT2A (0.52) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL5265873 | 0.79 | PKLR (0.52) | MEN1KMT2AGAAMMP2HPGD | |
| SCHEMBL5270590 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AGAAMMP2ALDH1A1 | |
| SCHEMBL5266801 | 0.77 | GPR27 (0.54) | MEN1KMT2AGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |