Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267185 | 0.90 | POLB (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5266469 | 0.87 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5272569 | 0.86 | MAPT (0.58) | RAB9ANPC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL5268734 | 0.86 | KDM4E (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5268958 | 0.86 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5269503 | 0.86 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5270533 | 0.85 | MEN1 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5269224 | 0.84 | KDM4E (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13816928 | 0.84 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5269702 | 0.83 | EPHX2 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |