Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270571 | 0.88 | KMT2A (0.59) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL5266006 | 0.87 | RAB9A (0.51) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5269503 | 0.85 | RAB9A (0.61) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5268958 | 0.83 | RAB9A (0.52) | SMN1; SMN2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL5266786 | 0.82 | MEN1 (0.54) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5270533 | 0.82 | MEN1 (0.47) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5267582 | 0.82 | LMNA (0.56) | SMN1; SMN2LMNAKMT2AMEN1RAB9A | |
| SCHEMBL5267166 | 0.82 | NPC1 (0.52) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL4281575 | 0.82 | RAB9A (0.48) | SMN1; SMN2MAPTKMT2AMEN1RAB9A | |
| SCHEMBL13816928 | 0.81 | RAB9A (0.54) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |