Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266786 | 0.91 | MEN1 (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC2 | |
| SCHEMBL5269246 | 0.90 | MLYCD (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC2 | |
| SCHEMBL5268235 | 0.90 | SMN1; SMN2 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5274230 | 0.87 | HPGD (0.49) | ALDH1A1HDAC2HDAC8HDAC6KMT2A | |
| SCHEMBL5268542 | 0.87 | TRPV1 (0.53) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5266006 | 0.86 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5270190 | 0.86 | LMNA (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC2 | |
| SCHEMBL4281575 | 0.86 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13816928 | 0.85 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC2 | |
| SCHEMBL5274237 | 0.83 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |