Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268485 | 0.92 | KCNA5 (0.51) | ALDH1A1CXCR4KCNA5MAPTTP53 | |
| SCHEMBL5269046 | 0.90 | KCNA5 (0.50) | ALDH1A1KCNA5MAPTMEN1KMT2A | |
| SCHEMBL5267731 | 0.89 | RAB9A (0.54) | ALDH1A1MAPTSMN1; SMN2SGMS1MEN1 | |
| SCHEMBL5267563 | 0.89 | KCNA5 (0.49) | ALDH1A1KCNA5MAPTTP53SMN1; SMN2 | |
| SCHEMBL5270827 | 0.89 | KMT2A (0.58) | ALDH1A1LMNAKCNA5MAPTTP53 | |
| SCHEMBL5268598 | 0.89 | KCNA5 (0.63) | ALDH1A1KCNA5MAPTTP53SGMS1 | |
| SCHEMBL5272580 | 0.88 | ALOX15 (0.49) | ALDH1A1KCNA5MAPTTP53MEN1 | |
| SCHEMBL5271844 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAKCNA5MAPTTP53 | |
| SCHEMBL5271580 | 0.86 | KCNA5 (0.47) | ALDH1A1KCNA5MAPTMEN1KMT2A | |
| SCHEMBL5270875 | 0.85 | HTT (0.50) | ALDH1A1KCNA5TP53SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |