Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268485 | 0.92 | KCNA5 (0.51) | KCNA5TP53MAPTGAAMEN1 | |
| SCHEMBL5269046 | 0.90 | KCNA5 (0.50) | KCNA5MAPTGAAMEN1KMT2A | |
| SCHEMBL5266973 | 0.89 | RAB9A (0.54) | MAPTSMN1; SMN2SGMS1ALDH1A1MCL1 | |
| SCHEMBL5270827 | 0.89 | KMT2A (0.58) | KCNA5TP53MAPTGAASMN1; SMN2 | |
| SCHEMBL5268598 | 0.89 | KCNA5 (0.63) | KCNA5TP53MAPTGAASGMS1 | |
| SCHEMBL5266472 | 0.89 | ALDH1A1 (0.53) | KCNA5TP53MAPTSMN1; SMN2SGMS1 | |
| SCHEMBL5272580 | 0.88 | ALOX15 (0.49) | KCNA5TP53MAPTGAAMEN1 | |
| SCHEMBL5271844 | 0.87 | ALDH1A1 (0.52) | KCNA5TP53MAPTGAASMN1; SMN2 | |
| SCHEMBL5271580 | 0.86 | KCNA5 (0.47) | KCNA5MAPTGAAMEN1KMT2A | |
| SCHEMBL5270875 | 0.85 | HTT (0.50) | KCNA5TP53GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |