Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269702 | 0.83 | EPHX2 (0.49) | MEN1KMT2AALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL5265952 | 0.83 | KMT2A (0.52) | MEN1KMT2AALDH1A1CDK2CCNE1 | |
| SCHEMBL5271648 | 0.82 | KMT2A (0.54) | MEN1KMT2AALDH1A1CDK2CCNE1 | |
| SCHEMBL5269233 | 0.82 | KMT2A (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5270533 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2ROCK2 | |
| SCHEMBL5268895 | 0.81 | LMNA (0.56) | MEN1KMT2AALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL5269272 | 0.80 | KDM4E (0.55) | MEN1KMT2AALDH1A1CDK2CCNA2 | |
| SCHEMBL5268228 | 0.80 | GAA (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5270583 | 0.79 | RAB9A (0.51) | MEN1KMT2AALDH1A1CDK2CCNE1 | |
| SCHEMBL5267757 | 0.79 | KMT2A (0.47) | MEN1KMT2AALDH1A1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |