Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267112 | 0.82 | NPC1 (0.48) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL5272564 | 0.81 | NPY4R (0.57) | GAAMAPK1ALDH1A1LMNANPC1 | |
| SCHEMBL5265952 | 0.80 | KMT2A (0.52) | KMT2AMEN1GAAPKMCDK2 | |
| SCHEMBL5271648 | 0.80 | KMT2A (0.54) | KMT2AMEN1PKMCDK2CCNE1 | |
| SCHEMBL5266503 | 0.79 | MEN1 (0.61) | KMT2AMEN1CDK2CCNE1CDK9 | |
| SCHEMBL5270089 | 0.79 | GAA (0.59) | KMT2AMEN1GAAPKMMAPK1 | |
| SCHEMBL5273651 | 0.78 | HRH3 (0.54) | KMT2AMEN1PKMCDK2CCNE1 | |
| SCHEMBL5271504 | 0.78 | HPGD (0.53) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL5268895 | 0.78 | LMNA (0.56) | KMT2AMEN1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL5269971 | 0.77 | L3MBTL1 (0.50) | KMT2AMEN1GAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |