Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268434 | 0.91 | TAAR1 (0.64) | MAPTTAAR1KDM4EGAAALDH1A1 | |
| SCHEMBL5271885 | 0.87 | MAPT (0.55) | MAPTKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL5268206 | 0.85 | HPGD (0.53) | MAPTKDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5269183 | 0.85 | MAPT (0.55) | MAPTKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL5268895 | 0.81 | LMNA (0.56) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5268751 | 0.81 | LMNA (0.53) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL5268228 | 0.81 | GAA (0.54) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL5267185 | 0.80 | POLB (0.48) | MAPTKDM4EGAAALDH1A1NPC1 | |
| SCHEMBL5270571 | 0.79 | KMT2A (0.59) | GAAALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL5270246 | 0.78 | NPC1 (0.57) | MAPTGAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |