Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268095 | 0.91 | MAPT (0.53) | TAAR1ALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL5271885 | 0.84 | MAPT (0.55) | ALDH1A1HSD17B10MAPTLMNATSHR | |
| SCHEMBL5269183 | 0.82 | MAPT (0.55) | ALDH1A1HSD17B10MAPTLMNATSHR | |
| SCHEMBL5266006 | 0.82 | RAB9A (0.51) | POLBALDH1A1MAPTLMNANPC1 | |
| SCHEMBL5270533 | 0.81 | MEN1 (0.47) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL5272692 | 0.81 | SIRT1 (0.54) | ALDH1A1HSD17B10MAPTLMNANPC1 | |
| SCHEMBL5268206 | 0.80 | HPGD (0.53) | POLBALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL5269503 | 0.80 | RAB9A (0.61) | POLBALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL5268228 | 0.80 | GAA (0.54) | POLBALDH1A1MAPTLMNATSHR | |
| SCHEMBL5266469 | 0.79 | SMN1; SMN2 (0.56) | TAAR1ALDH1A1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |