Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272692 | 0.92 | SIRT1 (0.54) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5268260 | 0.88 | MAPT (0.51) | LMNAMAPTKMT2AMEN1STAT3 | |
| SCHEMBL2930131 | 0.88 | MAPT (0.55) | LMNASMN1; SMN2MAPTKMT2ASLC6A2 | |
| SCHEMBL5266468 | 0.86 | POLB (0.58) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5272614 | 0.85 | CYP1A2 (0.53) | LMNAMAPTKMT2AMEN1STAT3 | |
| SCHEMBL954893 | 0.82 | ALDH1A1 (0.50) | LMNAMAPTKMT2AMEN1STAT3 | |
| SCHEMBL5270583 | 0.82 | RAB9A (0.51) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5268895 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2KMT2ASLC6A2MEN1 | |
| SCHEMBL5268095 | 0.81 | MAPT (0.53) | LMNAMAPTKMT2AMEN1RAB9A | |
| SCHEMBL5267185 | 0.80 | POLB (0.48) | LMNASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |