Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828165 | 0.79 | LMNA (0.39) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL9337194 | 0.79 | ALDH1A1 (0.40) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL5271146 | 0.74 | ALDH1A1 (0.42) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL828578 | 0.72 | ALDH1A1 (0.40) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL10948791 | 0.71 | ALDH1A1 (0.44) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL825848 | 0.70 | TNF (0.37) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL11681674 | 0.67 | LMNA (0.37) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL6231307 | 0.66 | MAPT (0.47) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL11684936 | 0.66 | LMNA (0.36) | LMNAGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL11681389 | 0.66 | LMNA (0.36) | LMNAGAAPOLBALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431315-B1 | Photopolymerization initiator and photopolymerizable composition | TOKUYAMA CORP (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-7041714-B2 | Dental adhesive | TOKUYAMA CORPORATION (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20040186195-A1 | Photopolymerization initiator and photopolymerizable composition | TOKUYAMA CORPORATION (JP) | 2004-09-23 | — | — | US | disclosed |
| EP-1431315-A2 | Photopolymerization initiator and photopolymerizable composition | Tokuyama Corporation (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040077746-A1 | Adhesives for dental use | TOKUYAMA CORPORATION (JP) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077746-A1 | Adhesives for dental use | ICAM1, CDH1, VCAM1 | LMNA 3337/4885GAA 4293/4885POLB 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.