SCHEMBL5268910

SCHEMBL5268910

CCCCCCCCCc1c(O)c(O)c(C(=O)O)c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.58
LDHB P07195 3/20 0.58
BID P55957 3/20 0.51
MCL1 Q07820 3/20 0.51
KAT8 Q9H7Z6 3/20 0.51
BCL2L1 Q07817 2/20 0.51
BAK1 Q16611 2/20 0.51
EP300 Q09472 2/20 0.51
KAT5 Q92993 2/20 0.51
SAE1 Q9UBE0 2/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
KAT2A Q92830 1/20 0.51
KAT2B Q92831 1/20 0.51
KDM4E B2RXH2 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 1/20 0.48
MMP2 P08253 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5272893 1.00 LDHA (0.58) LDHALDHBBIDMCL1KAT8
SCHEMBL5271907 1.00 LDHA (0.58) LDHALDHBBIDMCL1KAT8
SCHEMBL5270735 1.00 LDHA (0.58) LDHALDHBBIDMCL1KAT8
SCHEMBL5275544 1.00 LDHA (0.58) LDHALDHBBIDMCL1KAT8
SCHEMBL5272398 1.00 LDHA (0.58) LDHALDHBBIDMCL1KAT8
SCHEMBL29138979 0.86 BID (0.54) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL25261007 0.85 BID (0.50) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL1176170 0.85 BID (0.50) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL7594362 0.83 BID (0.48) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL168254 0.82 BID (0.48) BIDMCL1KAT8BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243609-B1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO (JP) 2007-10-24 EP disclosed
US-6906191-B2 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2005-06-14 US disclosed
US-20030018198-A1 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2003-01-23 US disclosed
EP-1243609-A1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2002-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018198-A1 Succinimide compounds and use thereof SRM, SMS, SGMS2 LDHA 552/4885LDHB 598/4885BID 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.