Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271535 | 0.87 | SLC40A1 (0.49) | POLBSLC40A1RELAKMT2AHPGD | |
| SCHEMBL5272917 | 0.84 | RAB9A (0.57) | POLBKMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL5265901 | 0.83 | SLC40A1 (0.53) | SLC40A1RELAKMT2AALDH1A1RAB9A | |
| SCHEMBL5269033 | 0.82 | RAB9A (0.49) | POLBSLC40A1RELAKMT2ARAB9A | |
| SCHEMBL5274156 | 0.77 | SLC40A1 (0.48) | SLC40A1RELAKMT2AALDH1A1HPGD | |
| SCHEMBL4287032 | 0.77 | HPGD (0.58) | POLBRELAKMT2AALDH1A1HPGD | |
| SCHEMBL5269055 | 0.77 | TSHR (0.57) | POLBKMT2AALDH1A1HPGDPKM | |
| SCHEMBL5269276 | 0.77 | ALDH1A1 (0.53) | POLBKMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL5268265 | 0.77 | TDP1 (0.47) | POLBALDH1A1HPGDPKMHSD17B10 | |
| SCHEMBL5269115 | 0.76 | HPGD (0.48) | POLBKMT2AALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |