Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274156 | 0.86 | SLC40A1 (0.48) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5271535 | 0.85 | SLC40A1 (0.49) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5269033 | 0.84 | RAB9A (0.49) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5269337 | 0.84 | SLC40A1 (0.49) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5268978 | 0.83 | POLB (0.53) | SLC40A1RELASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5270408 | 0.81 | LMNA (0.49) | MAPTSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL4195217 | 0.73 | SLC40A1 (0.59) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4195221 | 0.72 | SLC40A1 (0.64) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10576899 | 0.72 | SLC40A1 (0.64) | SLC40A1RELAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5269789 | 0.71 | MEN1 (0.51) | MAPTSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |