Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | MAP2 | P11137 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273891 | 0.88 | KDM4E (0.51) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5270273 | 0.88 | MAP2 (0.55) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5373358 | 0.86 | MAP2 (0.42) | JAK2MAP2ALDH1A1HPGDKDM4E | |
| SCHEMBL5273364 | 0.83 | KDM4E (0.44) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5272029 | 0.81 | GPR35 (0.48) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5274251 | 0.78 | MAPT (0.45) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5343866 | 0.76 | GPR35 (0.48) | GPR35 | |
| SCHEMBL5210645 | 0.76 | KDM4E (0.45) | JAK2MAP2ALDH1A1HPGDKDM4E | |
| SCHEMBL5334971 | 0.75 | ALDH1A1 (0.61) | MAP2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL5270236 | 0.75 | GPR17 (0.43) | ALDH1A1HPGDKDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |