Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 7/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273364 | 0.89 | KDM4E (0.44) | MAP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5269262 | 0.86 | JAK2 (0.51) | MAP2JAK2ALDH1A1HPGDKDM4E | |
| SCHEMBL5273163 | 0.85 | PRKAB2 (0.36) | JAK2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5273891 | 0.81 | KDM4E (0.51) | MAP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5270236 | 0.81 | GPR17 (0.43) | ALDH1A1HPGDKDM4EMEN1HTT | |
| SCHEMBL5270273 | 0.81 | MAP2 (0.55) | MAP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5271483 | 0.81 | RORC (0.36) | JAK2KDM4EMEN1KMT2APRKAB2 | |
| SCHEMBL5272029 | 0.80 | GPR35 (0.48) | MAP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5343008 | 0.79 | GPR17 (0.44) | ALDH1A1HPGDKDM4EMEN1HTT | |
| SCHEMBL5269374 | 0.77 | FFAR4 (0.36) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |