Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273262 | 0.83 | ADORA3 (0.53) | ADORA1ADORA3ADORA2AP2RY12ADORA2B | |
| SCHEMBL4259792 | 0.83 | RARB (0.53) | PLA2G2ARARBDHODHRARAP2RY12 | |
| SCHEMBL4267602 | 0.81 | ADORA1 (0.49) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL4263649 | 0.80 | ADORA1 (0.48) | PLA2G2AADORA1ADORA3RARBADORA2A | |
| SCHEMBL4265091 | 0.80 | P2RY12 (0.49) | PLA2G2ARARBDHODHRARAP2RY12 | |
| SCHEMBL4264916 | 0.79 | XDH (0.46) | PLA2G2ARARBDHODHRARANPC1 | |
| SCHEMBL4263343 | 0.77 | MCL1 (0.52) | ADORA1ADORA3ADORA2AP2RY12ADORA2B | |
| SCHEMBL4260900 | 0.77 | RARB (0.44) | PLA2G2AADORA1RARBDHODHRARA | |
| SCHEMBL13952546 | 0.74 | ADORA3 (0.52) | PLA2G2AADORA1ADORA3ADORA2AP2RY12 | |
| SCHEMBL14802124 | 0.73 | LTA4H (0.53) | PLA2G2AADORA3DHODHNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |