SCHEMBL5269733

SCHEMBL5269733

CCC(c1ccccc1/C=C/C(=O)O)[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.44
GAA P10253 3/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 2/20 0.43
NFKB1 P19838 1/20 0.43
HTT P42858 1/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
PTGER4 P35408 5/20 0.41
PTGER3 P43115 5/20 0.41
PTGER2 P43116 5/20 0.41
PTGER1 P34995 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2010382 0.88 NOS3 (0.40) KDM4EALDH1A1NOS3NOS1NOS2
SCHEMBL20566315 0.77 CA1 (0.50) KDM4EALDH1A1GAACA1CA2
SCHEMBL28414685 0.76 CA1 (0.56) KDM4EALDH1A1GAACA1CA2
SCHEMBL819054 0.76 CA1 (0.56) KDM4EALDH1A1GAACA1CA2
SCHEMBL1639304 0.75 TSHR (0.42) KDM4EMEN1KMT2ALMNA
SCHEMBL5269742 0.75 KDM4E (0.54) KDM4EALDH1A1CA1CA2CA4
SCHEMBL8575018 0.75 CA1 (0.55) KDM4EALDH1A1GAACA1CA2
SCHEMBL6851902 0.74 CA1 (0.47) KDM4EALDH1A1GAACA1CA2
SCHEMBL12930761 0.74 KDM4E (0.50) KDM4EGAACA1CA2CA4
SCHEMBL9354460 0.74 CA1 (0.47) KDM4EALDH1A1GAACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
EP-0896502-B1 Method of treating metal foil for enhancing adhesion NIKKO MATERIALS USA INC (US) 2007-10-03 EP disclosed
EP-0974685-B1 Method for making a metal foil with improved bonding to substrates GA TEK INC (US) 2003-12-03 EP disclosed
EP-1089866-A4 PROCESS TO PREPARE A POLYMER NANOCOMPOSITE COMPOSITION SOLUTIA INC (US) 2002-09-25 EP disclosed
EP-1214356-A1 METHODS FOR THE PREPARATION OF POLYAMIDE NANOCOMPOSITE COMPOSITIONS BY IN SITU POLYMERIZATION Solutia Inc. (US) 2002-06-19 EP disclosed
EP-1054922-A4 POLYMER NANOCOMPOSITE COMPOSITION SOLUTIA INC (US) 2001-08-08 EP disclosed
EP-1089866-A1 PROCESS TO PREPARE A POLYMER NANOCOMPOSITE COMPOSITION Solutia Inc. (US) 2001-04-11 EP disclosed
EP-1086144-A1 METHODS FOR THE PREPARATION OF POLYAMIDE NANOCOMPOSITE COMPOSITIONS BY IN SITU AND SOLID STATE POLYMERIZATIONS Solutia Inc. (US) 2001-03-28 EP disclosed
WO-2001012678-A1 METHODS FOR THE PREPARATION OF POLYAMIDE NANOCOMPOSITE COMPOSITIONS BY IN SITU POLYMERIZATION SOLUTIA INC. (US) 2001-02-22 WO disclosed
EP-1054922-A1 POLYMER NANOCOMPOSITE COMPOSITION Solutia Inc. (US) 2000-11-29 EP disclosed
US-5885436-A Adhesion enhancement for metal foil GOULD ELECTRONICS INC. (US) 1999-03-23 US disclosed
EP-0896502-A1 Method of treating metal foil for enhancing adhesion Gould Electronics Inc. (US) 1999-02-10 EP disclosed
US-5747560-A AMMONIUM SALTS ALLIEDSIGNAL INC. (US) 1998-05-05 US disclosed
EP-0598836-B1 MELT PROCESS FORMATION OF POLYMER NANOCOMPOSITE OF EXFOLIATED LAYERED MATERIAL ALLIED SIGNAL INC (US) 1997-10-15 EP disclosed
EP-0668888-A1 NANOCOMPOSITES OF GAMMA PHASE POLYMERS AlliedSignal Inc. (US) 1995-08-30 EP disclosed
US-5385776-A Polylactams ALLIEDSIGNAL INC. 1995-01-31 US disclosed
EP-0598836-A1 MELT PROCESS FORMATION OF POLYMER NANOCOMPOSITE OF EXFOLIATED LAYERED MATERIAL. ALLIED SIGNAL INC (US) 1994-06-01 EP disclosed
WO-1994011430-A1 NANOCOMPOSITES OF GAMMA PHASE POLYMERS ALLIED-SIGNAL INC. (US) 1994-05-26 WO disclosed
WO-1993004117-A1 MELT PROCESS FORMATION OF POLYMER NANOCOMPOSITE OF EXFOLIATED LAYERED MATERIAL ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
WO-1993004118-A1 MELT PROCESS FORMATION OF POLYMER NANOCOMPOSITE OF EXFOLIATED LAYERED MATERIAL ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed