Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271610 | 0.86 | MEN1 (0.57) | HTTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL5271810 | 0.86 | KCNA5 (0.50) | L3MBTL1GAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5268738 | 0.85 | METAP2 (0.44) | HTTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL5265268 | 0.84 | KCNA5 (0.46) | HTTGAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5271084 | 0.84 | LMNA (0.53) | HTTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL5269927 | 0.84 | LMNA (0.49) | HTTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL5272349 | 0.83 | MEN1 (0.47) | HTTGAAMAPK1MEN1KMT2A | |
| SCHEMBL5271118 | 0.83 | KMT2A (0.44) | HTTL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL5266724 | 0.82 | MCL1 (0.40) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5265743 | 0.81 | ALDH1A1 (0.53) | HTTL3MBTL1GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |