Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272349 | 0.93 | MEN1 (0.47) | KCNA5FPR1KMT2AMEN1HTT | |
| SCHEMBL5271810 | 0.89 | KCNA5 (0.50) | KCNA5SMN1; SMN2FPR1KDM4EALDH1A1 | |
| SCHEMBL5268738 | 0.88 | METAP2 (0.44) | SMN1; SMN2KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL5318573 | 0.87 | SLC40A1 (0.49) | KCNA5SMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL5269927 | 0.86 | LMNA (0.49) | KCNA5SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL5268976 | 0.86 | MEN1 (0.49) | SMN1; SMN2KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL5271118 | 0.85 | KMT2A (0.44) | SMN1; SMN2KMT2AALDH1A1MEN1HTT | |
| SCHEMBL5266724 | 0.84 | MCL1 (0.40) | KCNA5SMN1; SMN2CYP1A2FPR1KDM4E | |
| SCHEMBL5269964 | 0.84 | HTT (0.50) | SMN1; SMN2KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL5270764 | 0.83 | KMT2A (0.52) | SMN1; SMN2KDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |