SCHEMBL5273637

SCHEMBL5273637

CCn1nnc(F)c1[N+](=O)[O-]

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
TOP2A P11388 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SLC9A1 P19634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279426 0.86 TOP2A (0.36) TOP2AALDH1A1SLC9A1
SCHEMBL5277083 0.83 TOP2A (0.38) TOP2AALDH1A1SLC9A1
SCHEMBL5279908 0.80 SLC9A1 (0.40) TOP2AALDH1A1SLC9A1
SCHEMBL5289718 0.79 GRM2 (0.35) NPC1TOP2AALDH1A1SLC9A1
SCHEMBL5284830 0.79 ALDH1A1 (0.36) NPC1TOP2AALDH1A1SLC9A1
SCHEMBL5282394 0.79 NPC1 (0.34) NPC1TOP2AALDH1A1SLC9A1
SCHEMBL5282121 0.78 NPC1 (0.33) NPC1ALDH1A1SLC9A1
SCHEMBL5276637 0.78 NPC1 (0.33) NPC1ALDH1A1SLC9A1
SCHEMBL5278824 0.77 ALDH1A1 (0.35) NPC1ALDH1A1
SCHEMBL5281565 0.75 MAPT (0.35) NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed