Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285281 | 0.85 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL5286658 | 0.82 | SLC9A1 (0.38) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL5281132 | 0.81 | SMN1; SMN2 (0.36) | NPC1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5284830 | 0.81 | ALDH1A1 (0.36) | NPC1ALDH1A1SMN1; SMN2MAPTSLC9A1 | |
| SCHEMBL5289718 | 0.81 | GRM2 (0.35) | NPC1ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5288803 | 0.80 | SLC9A1 (0.41) | ALDH1A1LMNAMAPTKMT2ASLC9A1 | |
| SCHEMBL5276783 | 0.79 | MAPT (0.35) | NPC1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5277744 | 0.79 | GRIA1 (0.34) | NPC1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5273637 | 0.79 | NPC1 (0.33) | NPC1ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5276637 | 0.79 | NPC1 (0.33) | NPC1ALDH1A1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |