Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283087 | 0.85 | GRM2 (0.38) | GRM2ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5284602 | 0.82 | GRM2 (0.41) | GRM2NPC1ALDH1A1SLC9A1RAB9A | |
| SCHEMBL5282394 | 0.81 | NPC1 (0.34) | NPC1ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5284830 | 0.81 | ALDH1A1 (0.36) | NPC1ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5273507 | 0.80 | SLC9A1 (0.41) | GRM2ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5276637 | 0.79 | NPC1 (0.33) | NPC1ALDH1A1SLC9A1 | |
| SCHEMBL5273637 | 0.79 | NPC1 (0.33) | NPC1ALDH1A1SLC9A1TOP2A | |
| SCHEMBL5282121 | 0.79 | NPC1 (0.33) | NPC1ALDH1A1SLC9A1 | |
| SCHEMBL5281565 | 0.77 | MAPT (0.35) | NPC1ALDH1A1 | |
| SCHEMBL5282533 | 0.77 | LMNA (0.33) | NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |