Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274499 | 0.88 | KMT2A (0.46) | SMN1; SMN2ALDH1A1CNR1TSHRPOLB | |
| SCHEMBL5268958 | 0.83 | RAB9A (0.52) | RAB9ASMN1; SMN2ALDH1A1NPC1MEN1 | |
| SCHEMBL5266006 | 0.82 | RAB9A (0.51) | RAB9ASMN1; SMN2ALDH1A1NPC1POLB | |
| SCHEMBL5268199 | 0.81 | POLB (0.56) | SMN1; SMN2ALDH1A1POLBMEN1GAA | |
| SCHEMBL5266828 | 0.81 | KMT2A (0.48) | SMN1; SMN2ALDH1A1POLBHTTMEN1 | |
| SCHEMBL13816928 | 0.81 | RAB9A (0.54) | RAB9ASMN1; SMN2ALDH1A1NPC1TSHR | |
| SCHEMBL5272554 | 0.80 | KMT2A (0.47) | SMN1; SMN2ALDH1A1POLBHTTMEN1 | |
| SCHEMBL5266469 | 0.80 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2ALDH1A1NPC1MEN1 | |
| SCHEMBL4281575 | 0.80 | RAB9A (0.48) | RAB9ASMN1; SMN2ALDH1A1NPC1HTT | |
| SCHEMBL5269503 | 0.79 | RAB9A (0.61) | RAB9ASMN1; SMN2ALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |