Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528811 | 0.82 | ABCB1 (0.48) | HSD17B1HSD17B2CYP3A4CYP2C9DRD2 | |
| SCHEMBL5274700 | 0.81 | ESR1 (0.53) | CYP3A4CYP2C9ESR1ESR2CYP1A2 | |
| SCHEMBL28517648 | 0.79 | HSD17B1 (0.46) | HSD17B1HSD17B2CYP3A4CYP2C9DRD2 | |
| SCHEMBL29137601 | 0.78 | ALDH1A1 (0.45) | JUN | |
| SCHEMBL28008071 | 0.77 | OPRK1 (0.49) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL5607015 | 0.77 | ESR1 (0.37) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| Propane SCHEMBL5843489 | 0.75 | HSD17B1 (0.71) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL4779452 | 0.75 | HSD17B1 (0.64) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL25146909 | 0.75 | ESR2 (0.49) | HSD17B1HSD17B2CYP3A4CYP2C9DRD2 | |
| SCHEMBL27559833 | 0.74 | HSD17B1 (0.63) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504048-B1 | METHOD OF PREPARING POLYESTERCARBONATES | GEN ELECTRIC (US) | 2007-11-21 | — | — | EP | claimed |